Indications:

Nervous sleeping disorders and insomnia

Nervous spasms

Nervous asthma

Nervous tachycardia

PHARMACOLOGIC ACTIONS

Sleeping disorder, affecting about one-third of the adult population worldwide, is characterized as the inability to get the desired quality of sleep. The herbs in this product have been proven to shorten the time it takes to fall asleep, reduce the amount of awaking time after sleep onset, increase the length of deep sleep and improve sleep quality. This natural product has the added advantage over conventional sleeping drugs of no drowsiness or hangover type feelings the next day. It will also not interfere with driving abilities or work capacity.

ACTIVE INGREDIENTS

Each coated tablet contains:

valeriana officinalis root extract 150 mg

Passiflora incarnata aerial part extract 100 mg

Melissa officinalis leaf 50 mg

Hummulus lupulus female inflorescence 50 mg

ADMINISTRATION AND DOSAGE

For sleep onset and sleep maintenance insomnia: take 1 to 2 tablets about an hour before bedtime.

For other disorders: take 1 tablet up to 3 times daily.

INTERACTIONS

The sedative action may potentiate the effect of existing sedative therapy; therefore concomitant administration with other CNS depressants should be avoided.

ADVERSE REACTIONS

It is not recommended in patients who are sensitive to any of the component in this product. There is no reported side effect, although possible adverse effects include gastrointestinal disorders and headache.

CONTRAINDICATIONS & PRECAUTIONS

It is not recommended in patients suffering from depressive illness.

PREGNANCY AND LACTATION

It is not recommended during pregnancy and lactation.

STORAGE

Store below 30˚C and protect from moisture and light.

IRC

1228107979

REFERENCES

1-PDR for herbal medicine, 2005.

2-The Complete German Commission E monograph, 1998.

3-The ABC clinical guide to herbs, 2003.

4-Newall. C.A. Herbal medicine, a guide for health-care professionals, 1996.

5-Serafini M, Ghiselli A, Ferro-Luzzi. In vivo antioxidant effect of green and black tea in man. European journal of clinical nutrition. 1996. Vol.50 (1):28-32.

6-Sharma M., Jain U. K., Patel A and Gupta N. A comprehensive pharmacognostic report on valerian. International journal of pharmaceutical sciences and research. 2010. 1(7):6-40.

7-Andreatini R., Sartori V.A., Seabra M.L., Leite J.R. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo controlled pilot study. Phytotherapy Research. 2002. 16:650-4.

8-Kennedy D.O., Little W., Crystal F Haskell C.F., Scholey A.B. Anxiolytic effects of a combination of Melissa ofcinalis and Valeriana ofcinalis during laboratory induced stress. Phytotherapy Research. 2006. 20(2):96–102.