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Dosage Instructions

Pharmacological and Clinical Notes of Gripe Water

The essential oils present in this product, through a local effect on the mucous membrane of the gastric wall, rapidly increase vagus nerve activity and consequently enhance the intensity of gastric motility. This action facilitates the expulsion of gases caused by flatulence, increases gastrointestinal secretions, relieves flatulence, accelerates the digestion of food, and prevents food fermentation and gas formation. One of the advantages of Dineh Gripe Water oral solution is that no alcohol, artificial flavorings, artificial sweeteners, or sodium bicarbonate (baking soda) are used in its formulation. This increases the safety margin of the product, especially for use in infants and children, since sodium bicarbonate, in addition to interfering with the absorption of folic acid and iron, is not suitable as an antacid in children under 6 years of age due to the immaturity of the gastrointestinal system.
Another advantage of Gripe Water is that the formulation contains natural spearmint essential oil as a flavoring agent, which, in addition to providing a pleasant taste and aroma, also has an anti-flatulent effect.

GripeWater Clinical Data (pdf)
GripeWater Clinical Data (image)

Each bottle of Gripe Water contains:

Active Ingredients:

Contains:

Amount

Anethum graveolens Volatile oil

0.2 mcl/1ml

0.001 ml/5ml

Carum carvi Volatile oil

0.2 mcl/1ml

0.001 ml/5ml

(Standardized on 0.8 mg carvone in 5 ml)
  • No alcohol
  • No baking soda (Sodium bicarbonate)
  • No artificial sweeteners
Other Ingredients:

  • Natural spearmint oil, Methyl hydroxyl benzoate, Propyl hydroxyl benzoate, Cremophor, Dextrose

dineh gripe water
dineh gripe water
bottles of gripe water
Dosage Instructions

Gripe Water Dosage Instructions

  • Infants: 2.5 mL

  • Children: 5 mL

  • Adults: 10 to 20 mL

The acceptable daily intake of carvone has been determined to be up to 1 mg per kilogram of the infant’s body weight.
please wash the measuring cup after use.

not to use if

Precautions and contraindications:

  • - For the essential oils mentioned, at the concentrations used in Gripe Water, no adverse effects have been reported.
  • - In diabetic patients, use the product under medical supervision.
  • - There is no contraindication for use during pregnancy and breastfeeding.

Pregnancy & Lactation

There is no contraindication in consultation with a doctor.
medication interactions

interactions

  • - No specific drug interactions have been reported.
  • - Consult a physician or pharmacist if taking other medications.
medicine effect on body

Side Effects

Due to the concentration of cumin, dill, and mint essential oils used in the grape water solution, no side effects have been reported.

Storage Conditions

  • - After use, tightly close the bottle cap and store below 30°C, away from light and moisture.
  • - Keep out of reach of children.
  • - Maximum usage period after opening the bottle is 4 weeks.
  • The maximum period of use of the product after opening the bottle cap is 4 weeks.

Dineh Gripe Water "Active Ingredients"

best gripe waterdineh gripe water
Each 5 mL of Dineh Gripe Water oral solution contains natural essential oils from the seeds of *Anethum graveolens* (dill) and *Carum carvi* (caraway), equivalent to 0.8 mg of carvone. This product uses natural spearmint essential oil as a flavoring agent, which — in addition to its pleasant taste and aroma — also has therapeutic carminative (anti-flatulence) effects. Dineh Gripe Water is safe for infants, children, and adults alike, as it contains no alcohol, artificial flavoring, or baking soda (sodium bicarbonate).

Gripe Water "Frequently Asked Questions"

1What Is Colic in Infants?
All babies cry at different times and for different reasons — it’s how they communicate their needs. Colic, however, refers to crying in the first three months of life with no identifiable cause. It is one of the most distressing issues of the newborn period, hard on both the infant and the parents. Colic typically resolves by four months of age. What sets colic apart from ordinary crying is that each episode usually lasts more than three hours a day. The baby may be happy, alert, feeding, or even asleep — then suddenly begin crying, most often in the late afternoon or evening. Colicky crying is more intense and louder than normal crying. The infant may appear to be in pain or screaming. Soothing a colicky baby is difficult: the baby may calm down for short periods but remains unsettled the rest of the time, and the crying sometimes ends only after passing gas or having a bowel movement.
2What Is Colic Syrup For?
- Relieving infant colic (episodes of intense crying caused by abdominal discomfort).
- Improving digestion and reducing intestinal gas buildup.
- Calming and soothing unsettled infants and children suffering from bloating or stomach pain.
3Why Is Dineh Gripe Water the Best Syrup for Stomach Bloating?
To address uncomfortable gastrointestinal conditions, Dineh Iran Pharmaceuticals has formulated Gripe Water, an herbal syrup containing peppermint, caraway, and dill essential oils, to relieve the symptoms of abdominal cramps, stomach ache, and bloating (colic) in infants and children — and even adults. No harmful flavorings, artificial sweeteners, or alcohol were used in preparing this solution. Another key advantage of this herbal syrup is the absence of sodium bicarbonate (baking soda), which significantly increases the safety margin of Dineh Gripe Water oral solution, particularly for infants and young children. Sodium bicarbonate not only interferes with the absorption of folic acid and iron, but is also unsuitable for children under six years of age due to the immaturity of their digestive systems.
4What Are the Indications for Gripe Water Syrup?
- Gripe Water solution can be used for:
- Immediate relief of bloating in infants and children
- Fast relief of infant stomach ache
- Home treatment of infant stomach ache
- Treatment of infant abdominal cramps
- Relief of infant colic
- Relief of infant gas (intestinal gas)
- Anti-bloating syrup for infants
- Stomach ache syrup for 4-year-old children
- Stomach ache syrup for children aged 6
- Stomach ache syrup for children aged 8
- Treatment of stomach ache in children aged 10
- Alternative to imported infant anti-bloating syrups
- Alternative to gripe mixture syrups
5Is Gripe Water Also an Anti-Bloating Syrup for Adults?
Yes. Dineh Gripe Water herbal solution can be used as an anti-bloating remedy for infants, children, and adults alike, and serves as a fast-acting treatment for stomach bloating.
6Features of an Ideal Anti-Bloating Syrup for Children
- Free from harmful additives — suitable for newborns (typically from a few weeks or months of age) and young children for the relief of colic, bloating, and abdominal cramps.
- Reduces excess intestinal gas (treats bloating).
- Relieves abdominal pain and cramping caused by trapped gas.
- Calms colic-related fussiness and crying.
- Safe ingredients compatible with the sensitive digestive systems of infants, formulated to help expel gas bubbles.
- Contains herbal extbles.
- Contains herbal extracts such as fennel, dill, peppermint, and others — plants knowna soothing effect.
- Available as drops, a solution, or a syrup — typically naturally sweetened and free from artificial flavorings — for easy administration to children.
- Can be given by dropper or graduated spoon, usually after meals or at the onset of symptoms.
7A Natural Alternative to Synthetic Laxatives
For people who prefer to avoid synthetic laxatives, senna leaf syrup may be considered a natural option. Many people prefer herbal medicines because they perceive them as gentler and more compatible with the body's natural processes.
8A Suitable Diet for Relieving Constipation
Although senna leaf syrup can help relieve constipation on its own, it is generally better to adopt a broader approach that includes the following:
Adequate fluid intake: Drinking enough water can support the laxative effect and help prevent dehydration.
Diet: Eating a fiber-rich diet, including fruits, vegetables, and whole grains, can help maintain regular bowel function.
Lifestyle: Regular physical activity and daily exercise can help naturally stimulate digestion and bowel movements.

Dineh Gripe Water "Certification & References"

1. Iranian Herbal Pharmacopoeia, First Ed. (1381), 419-25, 506-11.
2. European Scientific Cooperative on Phytotherapy (E/S/C/O/P Monographs) Second Ed. (2003), 64-69.
3. Martindale, The Complete Drug Reference 38th Edition (2014), 2470, 2493-2621.
4. PDR for herbal medicines, Fourth Ed. (2008), 155-159, 256-57.

Dineh Gripe Water is licensed by the Iranian Food and Drug Administration (IFDA) with a valid IRC registration.
Iran Registration Code (IRC): 8074850203220967

DINEH Iran Industries Complex
Customer Support: 98-21-61018
dinehiran.com

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